Intravenous administration of puppy deciduous teeth stem cells in degenerative valve disease

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Intravenous administration of puppy deciduous teeth stem cells in degenerative valve disease

AIM The objective of this study is to investigate the improvement of heart function in dogs with chronic valvular heart disease after puppy deciduous teeth stem cells (pDSCs) administration. MATERIALS AND METHODS 20 client-owned dogs with degenerative valvular heart disease underwent multiple intravenous injections of allogeneic pDSCs. Dogs were randomly assigned to two groups: (i) Control gr...

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Therapeutic Benefit of Intra-articular Administration of Deciduous Teeth Stem Cells in Rabbit Model of Osteoarthritis

Background and Objective: Stem cell therapy is a new treatment option for osteoarthritis. A various applications of stem cell therapy have been used for cartilage regeneration in arthritis patient. The objective of this study was to examine therapeutic effects of puppy deciduous teeth stem cells for the treatment of osteoarthritis using a rabbit model. Methodology: In this study, rabbits were s...

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Isolation of Mesenchymal Stem Cells from Human Deciduous Teeth Pulp

This study aimed to identify predictors of success rate of mesenchymal stem cell (MSC) isolation from human deciduous teeth pulp. A total of 161 deciduous teeth were extracted at the dental clinic of Chang Gung Memorial Hospital. The MSCs were isolated from dental pulps using a standard protocol. In total, 128 colonies of MSCs were obtained and the success rate was 79.5%. Compared to teeth not ...

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Biological characteristics of Stem Cells from Human Exfoliated Deciduous Teeth (SHEDs) and its therapeutic applications in regenerative medicine

Stem cells isolated from human exfoliated deciduous teeth (SHEDs) are multipotent mesenchymal stem cells that are isolated from dental pulp tissues. These cells have a high proliferative capacity, multipotential ability, immunomodulatory function, and minimal risk of oncogenesis. Recent studies have shown that SHEDs are a feasible cell source for cell therapy and regenerative medicine.

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SHED: stem cells from human exfoliated deciduous teeth.

To isolate high-quality human postnatal stem cells from accessible resources is an important goal for stem-cell research. In this study we found that exfoliated human deciduous tooth contains multipotent stem cells [stem cells from human exfoliated deciduous teeth (SHED)]. SHED were identified to be a population of highly proliferative, clonogenic cells capable of differentiating into a variety...

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ژورنال

عنوان ژورنال: Veterinary World

سال: 2016

ISSN: 0972-8988,2231-0916

DOI: 10.14202/vetworld.2016.1429-1434